Starting Dose Guide
Duloxetine Starting Dose — What to Expect
Always follow your prescriber's specific dosing instructions. Starting doses vary based on your individual health, age, weight, kidney function, and other medications. This is general guidance only.
Common Duloxetine Doses
20mg (typical start)30mg40mg60mg
Your prescriber will determine the right starting dose for you.
Starting Duloxetine — What to Expect Week by Week
- Week 1-2: Start at 20mg. Side effects are most common early — most improve significantly.
- Week 2-4: Your body adjusts. Report persistent or severe side effects to your prescriber.
- Week 4-6: First follow-up appointment — prescriber evaluates response and may adjust dose.
- Month 2+: Stable dosing established. Recheck at 3 months, then annually.