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    Home/Medications/Ibuprofen

    NSAIDs

    Ibuprofen

    Ibuprofen is an anti-inflammatory painkiller sold over the counter at 200 mg (Advil, Motrin IB and store brands) and on prescription as generic 400, 600 and 800 mg tablets. Its labels warn of heart attack, stroke and stomach bleeding; intravenous Caldolor is a hospital product.

    Written by the Script Unlock editorial teamLast updated October 7, 2026Not yet reviewed by an independent pharmacist

    This page is general information about a medication and how cash prices for it are set. It is not medical advice and does not replace the label, your prescriber or your pharmacist. How we handle medical information

    Get cash quotes for Ibuprofen
    Brand names
    Advil, Motrin, Caldolor
    Generic available in the US
    Yes
    Dosage forms
    Prescription tablets; Oral suspension and infant drops; Over-the-counter tablets and capsules; Tablets with famotidine; Intravenous injection (Caldolor, hospital use)
    Strengths on US labels
    400, 600 and 800 mg prescription tablets; 200 mg over-the-counter tablets and capsules; Suspension 100 mg per 5 mL; infant drops 50 mg per 1.25 mL
    Commonly prescribed for
    Pain, Fever, Inflammation, Arthritis, Menstrual Cramps

    Prescription tablets have many generic makers; store-brand 200 mg products contain the same medicine as Advil and Motrin IB.

    About Ibuprofen

    Ibuprofen blocks the COX enzymes that make prostaglandins, which drive pain, swelling and fever. Prescription strengths are labeled for rheumatoid arthritis and osteoarthritis, up to 3,200 mg a day, and for mild to moderate pain and period pain; over-the-counter products are for minor aches and fever.

    Like every prescription NSAID, it carries boxed warnings for two risks. It raises the risk of heart attack and stroke, which can start early in treatment and grows with longer use, and it must not be used around heart bypass surgery. It can cause bleeding, ulcers and perforation in the stomach or intestines, more often in older adults and people with past ulcers. Both can be fatal. It can also raise blood pressure, worsen heart failure and harm the kidneys. Anyone who has had asthma or hives after aspirin or another NSAID must not take it, and it is avoided from about 20 weeks of pregnancy.

    Prescription tablets are generic, as Motrin’s prescription tablets are discontinued, and a prescription suspension is also made. Over the counter there are 200 mg tablets and capsules, children’s suspension and infant drops; the Drug Facts limit adults to six tablets in 24 hours unless a doctor directs, and say to ask a doctor if pain lasts beyond 10 days or fever beyond 3. Caldolor, given into a vein, treats pain and fever from 3 months of age. A generic ibuprofen and famotidine tablet is also sold, though its Duexis brand is discontinued.

    Taking Ibuprofen

    How to take it
    Usually three or four times a day for arthritis, or every 4 to 6 hours as needed for pain, with food or milk if it upsets your stomach. Shake liquids well and measure with the device supplied. Use the lowest dose that works for the shortest time.
    If you miss a dose
    If you take it regularly, take a missed dose when you remember, unless the next one is nearly due; then skip it. Do not take a double dose.
    Storage
    At room temperature, tightly closed, away from excess heat and moisture (not in the bathroom), out of reach of children.
    Interactions to know about
    Aspirin, other NSAIDs, blood thinners, steroids and SSRI or SNRI antidepressants raise bleeding risk, and it can blunt the heart protection of low-dose aspirin. It can weaken blood pressure medicines and water pills and strain the kidneys with them, and raises lithium and methotrexate levels. Three or more alcoholic drinks a day add to stomach bleeding risk.

    This summarizes the official prescribing information. Your prescriber’s and pharmacist’s instructions, and the leaflet that comes with your medicine, take priority.

    Why the cash price for Ibuprofen differs from pharmacy to pharmacy

    Prescription tablets have many makers, so a quote is mostly the dispensing fee and pricing method; a flat-price list, a per-tablet price or a minimum charge can quote the same bottle very differently.

    Over-the-counter tablets carry no dispensing fee, and the famotidine combination has fewer makers and is quoted on its own terms.

    Have a Ibuprofen prescription?

    Upload it and licensed pharmacies reply with their own cash price. You pay the pharmacy, not us.

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    Ways to pay less for Ibuprofen without insurance

    • Ask whether ibuprofen is on the pharmacy’s flat-price generic list.
    • Ask the prescriber whether over-the-counter 200 mg tablets would do, since going beyond the package directions needs their instruction.
    • If prescribed the ibuprofen and famotidine tablet, ask for quotes on the two generics separately too.
    • For a child, ask whether over-the-counter suspension or drops would do.
    • Upload the prescription to Script Unlock so licensed pharmacies can quote their cash price. You pay the pharmacy directly.

    How Script Unlock gets you a cash price for Ibuprofen

    Prices on this site come from pharmacies responding to a real prescription. We do not publish estimated, average or "typical" prices, because none of those would be your price.

    1. 1You upload your prescription

      A photo of your Ibuprofen prescription is enough. Nothing is sold on the site; you are asking pharmacies to quote.

    2. 2Licensed pharmacies respond

      Pharmacies that Script Unlock has verified see the request and each can reply with its own cash price for your exact drug, strength and quantity.

    3. 3You choose and pay the pharmacy

      You compare the responses, pick a pharmacy, and pay that pharmacy directly when you collect. Script Unlock never takes a patient payment and never sets the price.

    Upload a Ibuprofen prescriptionWhat Script Unlock cannot do

    Questions to ask your pharmacist about Ibuprofen

    1. 1.Is it safe with my blood pressure, heart or kidney conditions?
    2. 2.Can I take it with low-dose aspirin, and how should I time them?
    3. 3.Does it interact with my blood thinner, antidepressant or lithium?
    4. 4.What stomach symptoms mean I should stop?
    5. 5.Is the over-the-counter strength enough for me?

    Related medications

    NaproxenMeloxicamCelecoxibDiclofenac

    Sources

    • FDA-approved labeling on DailyMed (ibuprofen)
    • FDA-approved labeling on DailyMed (Caldolor)
    • MedlinePlus drug information (National Library of Medicine)
    • FDA Orange Book (approved generics and therapeutic equivalence)

    Script Unlock is a marketplace that lets licensed pharmacies quote a cash price on your prescription. It does not prescribe, dispense or sell medication, does not process patient payments, and does not give medical advice. Always follow the instructions of your prescriber and pharmacist and read the medication guide supplied with your medicine.

    Get cash quotes for Ibuprofen
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    Upload your prescription and licensed, verified pharmacies each quote their own cash price. You pay the pharmacy directly.

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