Vitamins

    Vitamin DCholecalciferol/Ergocalciferol

    The FDA-approved prescription form of plain vitamin D is ergocalciferol (vitamin D2) in 50,000-unit capsules, a generic; vitamin D3 (cholecalciferol) is sold over the counter as a dietary supplement. The prescription capsule is inexpensive, so its cash price is mostly the pharmacy’s dispensing fee.

    Written by the Script Unlock editorial teamLast updated October 7, 2026Not yet reviewed by an independent pharmacist

    This page is general information about a medication and how cash prices for it are set. It is not medical advice and does not replace the label, your prescriber or your pharmacist. How we handle medical information

    Brand names
    Drisdol, Calciferol
    Generic available in the US
    Yes
    Dosage forms
    Capsules (prescription ergocalciferol, vitamin D2); Oral liquid (ergocalciferol, sold as a supplement); Tablets, capsules and liquids (vitamin D3, over the counter)
    Strengths on US labels
    50,000 units (1.25 mg) capsules; 8,000 units per mL liquid; Vitamin D3 in a wide range of strengths
    Commonly prescribed for
    Vitamin D Deficiency, Osteoporosis, Rickets

    Ergocalciferol capsules are made by several companies under FDA approval, alongside the Drisdol brand; no single-ingredient vitamin D3 product is FDA-approved.

    About Vitamin D

    Vitamin D helps the body absorb calcium and keep bones mineralized; too little causes rickets in children and soft, weak bones in adults. A deficiency is found with a blood test, and MedlinePlus describes treatment as vitamin D supplements, with the prescriber deciding how much, how often and for how long.

    The label for the 50,000-unit capsule lists three uses: hypoparathyroidism, rickets that does not respond to usual vitamin D, and familial hypophosphatemia. Clinicians also prescribe it outside the label to correct a deficiency, for example as one capsule a week for a set number of weeks followed by a lower maintenance dose. Over-the-counter D3 is a supplement, and the FDA does not approve supplements before they are sold. Both forms raise blood vitamin D levels; most evidence reviewed by the NIH finds that D3 raises them further and keeps them up longer.

    Too much vitamin D raises blood calcium, causing loss of appetite, nausea, weakness, constipation, thirst and frequent urination, and can damage the kidneys; the label notes the effects can last two months or more after stopping. It is not used with high blood calcium or vitamin D toxicity, and the label asks prescribers to count vitamin D from all sources and to check blood calcium. Some capsules contain the dye tartrazine.

    Taking Vitamin D

    How to take it
    On the schedule the prescriber sets, which may be daily or weekly depending on the reason. Swallow the capsule whole; do not chew or crush it. It works only if you also get enough calcium from food, and the prescriber may give diet advice.
    If you miss a dose
    Take it as soon as you remember, unless it is almost time for the next dose; then skip the missed dose and continue as usual. Do not take a double dose.
    Storage
    At room temperature in a closed container, away from light, heat and moisture, and out of reach of children.
    Interactions to know about
    Mineral oil reduces its absorption, and the weight-loss drug orlistat can lower vitamin D levels. In people with hypoparathyroidism, thiazide water pills taken with it can push calcium too high. Tell the prescriber about other vitamin D or calcium products, including multivitamins, and about kidney or liver disease.

    This summarizes the official prescribing information. Your prescriber’s and pharmacist’s instructions, and the leaflet that comes with your medicine, take priority.

    Why the cash price for Vitamin D differs from pharmacy to pharmacy

    Ergocalciferol capsules cost pharmacies very little each, so a cash quote is mostly the dispensing fee and depends on how the pharmacy prices cheap generics: a flat-price list, a per-capsule price or a minimum charge. A short course of weekly capsules carries the same fee as a large fill.

    Over-the-counter D3 is a shelf product with no dispensing fee; as a supplement, it is not FDA-approved.

    Have a Vitamin D prescription?

    Upload it and licensed pharmacies reply with their own cash price. You pay the pharmacy, not us.

    Get quotes

    Ways to pay less for Vitamin D without insurance

    • Ask whether ergocalciferol is on the pharmacy’s flat-price generic list.
    • If the prescriber has set a fixed course, ask for the whole course to be dispensed in one fill, so you pay one fee.
    • Ask the prescriber whether an over-the-counter product would suit you instead, and at what strength.
    • Upload the prescription to Script Unlock so licensed pharmacies can quote their cash price. You pay the pharmacy directly.

    How Script Unlock gets you a cash price for Vitamin D

    Prices on this site come from pharmacies responding to a real prescription. We do not publish estimated, average or "typical" prices, because none of those would be your price.

    1. 1You upload your prescription

      A photo of your Vitamin D prescription is enough. Nothing is sold on the site; you are asking pharmacies to quote.

    2. 2Licensed pharmacies respond

      Pharmacies that Script Unlock has verified see the request and each can reply with its own cash price for your exact drug, strength and quantity.

    3. 3You choose and pay the pharmacy

      You compare the responses, pick a pharmacy, and pay that pharmacy directly when you collect. Script Unlock never takes a patient payment and never sets the price.

    Questions to ask your pharmacist about Vitamin D

    1. 1.Is this vitamin D2 or D3, and how often do I take it?
    2. 2.How long should I take this strength, and when will my level be rechecked?
    3. 3.Should I keep taking my multivitamin or calcium alongside it?
    4. 4.Do any of my medicines, such as a water pill, interact with it?
    5. 5.Does this capsule contain tartrazine?

    Sources

    Script Unlock is a marketplace that lets licensed pharmacies quote a cash price on your prescription. It does not prescribe, dispense or sell medication, does not process patient payments, and does not give medical advice. Always follow the instructions of your prescriber and pharmacist and read the medication guide supplied with your medicine.