How much does Sertraline cost for Depression without insurance?

Sertraline for Depression costs from $5 per month when pharmacies compete on Script Unlock — saving up to 80% vs the retail price of $25. No insurance is required.

Is Sertraline effective for Depression?

Sertraline (Sertraline Hydrochloride) is a prescribed medication used in the treatment of Depression. Always consult your healthcare provider to determine if Sertraline is the right treatment for your specific situation.

Are there cheaper alternatives to Sertraline for Depression?

Yes. Script Unlock lets you compare all Depression medications side-by-side. Other options may include generic versions or alternative medications in the same drug class. Compare prices on our Depression medication page.

Depression Treatment

Sertraline for Depression

Compare Sertraline (Sertraline Hydrochloride) prices for Depression treatment. Cash pay from $5 when pharmacies compete on Script Unlock — no insurance required.

Retail price

$25

Script Unlock

from $5

You save

up to $20

Compare Sertraline Prices

Free · No account · HIPAA-compliant

About Sertraline for Depression

Sertraline is one of the most commonly prescribed antidepressants.

Brand Names

Zoloft

Common Doses

25mg, 50mg, 100mg

Generic Available

Yes

Common Sertraline Side Effects

Nausea (especially first 1-2 weeks)
Diarrhea
Dry mouth
Insomnia or drowsiness

Full Sertraline side effects guide →

Sertraline Price for Depression by State

Texas California Florida New York Georgia Pennsylvania Illinois Ohio

Other Depression Medications

Escitalopram Bupropion Fluoxetine

Why Script Unlock for Depression Medications

Compare all Depression medications in one place — not just Sertraline
Pharmacies actively bid for your prescription — prices go lower than any coupon
No insurance required — transparent cash prices from verified pharmacies
Includes independent and compounding pharmacies often excluded from GoodRx

Medical Disclaimer: This page is for informational purposes only. Always consult your healthcare provider before starting, stopping, or changing any medication for Depression.

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