CVS Pharmacy · Price Comparison 2026
Duloxetine at CVS Pharmacy: ~$261
CVS uses PBM-negotiated pricing. Cash prices vary but are often 40–60% above independent pharmacy rates. When independent pharmacies compete on Script Unlock, the same Duloxetine (Duloxetine Hydrochloride) is available from $72 — saving you $189 per fill.
CVS Pharmacy Price
~$261
typical cash price
Competing Pharmacies
From $72
when pharmacies compete
You Could Save
$189
vs CVS Pharmacy
Free · No account needed · Takes 30 seconds
Don't Pay CVS Pharmacy's $261 for Duloxetine
Pharmacies compete. You save $189. Takes 30 seconds.