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    Home/Medications/Insulin Glargine

    Long-Acting Insulin

    Insulin Glargine

    Insulin glargine is a long-acting basal insulin injected once a day to provide steady background insulin. It is sold as Lantus, Basaglar, Semglee, Rezvoglar and Toujeo, and unbranded versions exist.

    Written by the Script Unlock editorial teamLast updated September 27, 2026Not yet reviewed by an independent pharmacist

    This page is general information about a medication and how cash prices for it are set. It is not medical advice and does not replace the label, your prescriber or your pharmacist. How we handle medical information

    Brand names
    Lantus, Basaglar, Toujeo, Semglee
    Generic available in the US
    Yes
    Dosage forms
    Prefilled injection pen; Vial for use with insulin syringes
    Strengths on US labels
    100 units per mL (Lantus, Basaglar, Semglee, Rezvoglar, unbranded glargine); 300 units per mL (Toujeo)
    Commonly prescribed for
    Type 1 Diabetes, Type 2 Diabetes

    Semglee and Rezvoglar are interchangeable biosimilars for Lantus; unbranded insulin glargine is also sold. Toujeo has no interchangeable equivalent.

    About Insulin Glargine

    Insulin glargine is a modified human insulin designed to be absorbed slowly and evenly over about twenty-four hours. It is used in type 1 diabetes alongside mealtime insulin, and in type 2 diabetes when oral medicines and other injectables are not enough. The goal is a steady baseline that keeps fasting blood sugar in range without the peaks of older intermediate-acting insulins.

    The US market now has several versions. Lantus is the original. Basaglar is a follow-on product, and Semglee and Rezvoglar are approved as interchangeable biosimilars, which means a pharmacist may substitute one for Lantus without contacting the prescriber, subject to state law. Toujeo is a more concentrated form of glargine with a slightly different profile and is not interchangeable with the others.

    Because insulin is a biologic, generics do not exist in the traditional sense; the biosimilar route plays that role. Manufacturers have also introduced unbranded versions of their own insulins at a lower list price, and cash-pay programmes that cap what a patient pays per month.

    Why the cash price for Insulin Glargine differs from pharmacy to pharmacy

    Insulin pricing has several layers: the brand list price, the lower list price of the unbranded version of the same insulin, the biosimilar, and manufacturer cash-pay caps that apply only if the pharmacy processes them correctly. Two pharmacies can quote very different cash prices for what is functionally the same insulin depending on which of these routes they use.

    Pens cost more than vials for the same number of units, and a prescription written for a specific brand limits what the pharmacy can dispense. Whether the pharmacist can substitute the interchangeable biosimilar depends on how the prescription is written and on your state’s substitution rules.

    Ways to pay less for Insulin Glargine without insurance

    • Ask your prescriber to write for insulin glargine generically, or to allow substitution, so the pharmacy can dispense the biosimilar or unbranded version.
    • Ask the pharmacy about the manufacturer’s monthly cash-pay cap programme and whether they will apply it. The programmes exist for the major insulin brands but are not automatic.
    • If you are comfortable with syringes, ask whether a vial prescription would be cheaper than pens for your dose.
    • Never stretch or skip insulin doses to save money; talk to the prescriber first, because there is almost always a cheaper route to the same insulin.
    • Upload the prescription to Script Unlock so licensed pharmacies can quote a cash price for the exact product and quantity. You pay the pharmacy directly.

    How Script Unlock gets you a cash price for Insulin Glargine

    Prices on this site come from pharmacies responding to a real prescription. We do not publish estimated, average or "typical" prices, because none of those would be your price.

    1. 1You upload your prescription

      A photo of your Insulin Glargine prescription is enough. Nothing is sold on the site; you are asking pharmacies to quote.

    2. 2Licensed pharmacies respond

      Pharmacies that Script Unlock has verified see the request and each can reply with its own cash price for your exact drug, strength and quantity.

    3. 3You choose and pay the pharmacy

      You compare the responses, pick a pharmacy, and pay that pharmacy directly when you collect. Script Unlock never takes a patient payment and never sets the price.

    Upload a Insulin Glargine prescriptionWhat Script Unlock cannot do

    Questions to ask your pharmacist about Insulin Glargine

    1. 1.Is this Lantus, a biosimilar, or the unbranded version, and was substitution allowed?
    2. 2.How many units are in this package, and how many days will it last at my dose?
    3. 3.How should I store unopened and in-use pens or vials?
    4. 4.What should I do if I inject the wrong insulin by mistake?
    5. 5.Which pen needles or syringes match this product?

    Related medications

    MetforminSemaglutide

    Sources

    • FDA-approved labeling on DailyMed (insulin glargine)
    • FDA Purple Book (biologics, biosimilars and interchangeable products)
    • MedlinePlus drug information (National Library of Medicine)

    Script Unlock is a marketplace that lets licensed pharmacies quote a cash price on your prescription. It does not prescribe, dispense or sell medication, does not process patient payments, and does not give medical advice. Always follow the instructions of your prescriber and pharmacist and read the medication guide supplied with your medicine.

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    You pay the pharmacy directly
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    Upload your prescription and licensed, verified pharmacies each quote their own cash price. You pay the pharmacy directly.

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