Lubiprostone Side Effects
Common and serious side effects of Lubiprostone (Lubiprostone) — what to expect and how to manage them.
Common Side Effects
- Headache
- Diarrhea or constipation
- Nausea
- Stomach pain
- Gas or bloating
- Dry mouth
Serious Side Effects
Seek immediate care if severe- Vitamin B12 deficiency (PPIs long-term)
- C. diff infection
- Hypomagnesemia (PPIs long-term)
- Bone fractures (PPIs long-term)
- Kidney problems
Managing Side Effects
- Take PPIs 30-60 minutes before first meal for best effect
- Reassess need for PPI every 3-6 months
- B12 and magnesium monitoring for long-term PPI users
- H2 blockers can be used as needed (more flexible)
What Your Doctor May Monitor
Magnesium levels (PPIs)B12 levelsBone density (long-term PPIs)Kidney function
Lubiprostone Cash Price
Lubiprostone cash prices start from $210 when pharmacies compete on Script Unlock — up to 30% below retail. No insurance required.
Compare Lubiprostone PricesMedical Disclaimer: This information is for educational reference only. Side effects vary by individual, dose, and other medications. Always consult your healthcare provider for personalized medical advice. Do not stop or change your medication without medical guidance.