Bupropion XL Side Effects
Common and serious side effects of Bupropion XL (Bupropion extended-release) — what to expect and how to manage them.
Common Side Effects
- Nausea (especially first 1-2 weeks)
- Insomnia or drowsiness
- Dry mouth
- Headache
- Sexual dysfunction
- Weight changes
- Diarrhea or constipation
Serious Side Effects
Seek immediate care if severe- Suicidal thoughts (especially ages <25 — monitor closely)
- Serotonin syndrome (with other serotonergic drugs)
- Mania or hypomania
- Withdrawal syndrome if stopped abruptly
- Bleeding risk
Managing Side Effects
- Full effect takes 4-6 weeks — be patient
- Never stop abruptly — always taper
- Take at same time daily
- Report mood changes or unusual thoughts immediately
- Avoid alcohol
What Your Doctor May Monitor
Mood and suicidal ideationSleep patternsWeightSigns of serotonin syndrome
Bupropion XL Cash Price
Bupropion XL cash prices start from $30 when pharmacies compete on Script Unlock — up to 40% below retail. No insurance required.
Compare Bupropion XL PricesMedical Disclaimer: This information is for educational reference only. Side effects vary by individual, dose, and other medications. Always consult your healthcare provider for personalized medical advice. Do not stop or change your medication without medical guidance.