Naloxone Price in South Dakota — From $20 at Verified Pharmacies
Naloxone (Naloxone Hydrochloride) is one of the most-filled prescriptions in South Dakota. Cash prices vary dramatically by pharmacy — from $$20/month at competitive South Dakota independents to ~$$50/month at chain counter retail. This page shows the South Dakota price landscape, top-city pricing, pharmacy-type tradeoffs, and how to lock the lowest cash bid.
South Dakota Naloxone Price Landscape
A 30-day supply of Naloxone, priced four ways across the South Dakota pharmacy market.
| Source | South Dakota 30-day price | Notes |
|---|---|---|
| National chain retail (CVS/Walgreens) | $50/mo | Walk-in counter price |
| South Dakota chain with insurance copay | $28/mo | Tier 1/2 generic copay estimate |
| Major coupon platforms | $29/mo | Pre-set discount |
| ScriptUnlock — South Dakota winning bid | $20/mo | Live South Dakota pharmacy bid |
Annual South Dakota savings switching from chain retail to ScriptUnlock: ~$360/year on Naloxone alone.60% is the typical ScriptUnlock cash savings on naloxone hydrochloride against national retail.
Naloxone in Top South Dakota Cities
Drill into city-level Naloxone pharmacy bids — pharmacy density and average savings vary by metro.
South Dakota Pharmacy Types for Naloxone
Three pharmacy categories serve South Dakota; each has a different price profile for Naloxone.
South Dakota's independent pharmacies often have the lowest cash price for Naloxone. They source from regional wholesalers and don't carry chain overhead. Bids from independents typically beat chain coupons by 20–40% on cash-pay generics.
If your Naloxone requires a custom dose, alternate dosage form, or excipient-free formulation, South Dakota compounding pharmacies can prepare it. Compounders bid on ScriptUnlock too — useful for pediatric, geriatric or allergy-sensitive patients.
CVS, Walgreens, Walmart, Costco and HEB (in TX) maintain large South Dakota footprints. Cash prices vary widely — Walmart and Costco often beat CVS/Walgreens on generic Naloxone. ScriptUnlock surfaces the cheapest chain bid alongside independents.
Free · no signup · 180+ South Dakota pharmacies · live cash bids
Naloxone in South Dakota — FAQ
How much does Naloxone cost in South Dakota?+
Naloxone cash prices in South Dakota start from $20/month on ScriptUnlock when South Dakota pharmacies compete. Retail walk-in pricing averages $50/month at chains. Insurance copays for a Tier 1/2 generic typically run $28/month, which is often more expensive than the cash bid. Always compare both before filling.
Where is Naloxone cheapest in South Dakota?+
In South Dakota, Naloxone is usually cheapest at independent pharmacies that bid through ScriptUnlock. Walmart, Costco and HEB chain locations are also competitive on generic naloxone hydrochloride. The cheapest South Dakota pharmacy on any given day depends on live bids — pharmacies adjust pricing based on wholesale costs, inventory and demand.
Do I need insurance to get Naloxone in South Dakota?+
No. With 9.4% of South Dakota adults uninsured, cash-pay pricing is a major part of South Dakota's pharmacy economy. ScriptUnlock works without insurance — South Dakota pharmacies submit cash bids and you pay that price at pickup. For most generic medications, cash is cheaper than the insurance copay anyway.
How many South Dakota pharmacies carry Naloxone?+
South Dakota has approximately 180 licensed pharmacies, the vast majority of which can stock or order Naloxone. ScriptUnlock surfaces South Dakota pharmacies with verified stock and live cash bids — usually 30–80 within a 25-mile radius depending on your city.
Can I save more on Naloxone with a 90-day supply in South Dakota?+
Yes. South Dakota pharmacies routinely dispense 90-day supplies for stable, chronic Naloxone prescriptions. Cash pricing for 90-day fills is usually 10–20% cheaper per day than 30-day fills. Over a year, switching from 30-day to 90-day fills typically saves an extra $36–$53 on top of marketplace savings.
Related Naloxone & South Dakota Pages
SD pharmacy market · 180+ licensed locations