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    Apixaban

    Apixaban (Eliquis) is a twice-daily oral anticoagulant that prevents blood clots in people with atrial fibrillation and treats or prevents clots in the legs and lungs. It is brand-only in the United States, which is why it is one of the most expensive commonly prescribed tablets.

    Written by the Script Unlock editorial teamLast updated September 27, 2026Not yet reviewed by an independent pharmacist

    This page is general information about a medication and how cash prices for it are set. It is not medical advice and does not replace the label, your prescriber or your pharmacist. How we handle medical information

    Brand names
    Eliquis
    Generic available in the US
    No
    Dosage forms
    Tablet
    Strengths on US labels
    2.5 and 5 mg tablets
    Commonly prescribed for
    Atrial Fibrillation, DVT, Pulmonary Embolism, Blood Clot Prevention

    Approved generics exist on paper but are not marketed in the US yet. Do not buy apixaban from overseas websites; counterfeit anticoagulants are a documented problem.

    About Apixaban

    Apixaban directly blocks factor Xa, one of the key enzymes in the clotting cascade. Compared with warfarin it has a predictable effect, needs no routine blood monitoring, has fewer food interactions, and in trials caused less serious bleeding. It is taken twice a day at a fixed dose, with a reduced dose for people who meet specific age, weight and kidney criteria.

    It is approved to reduce stroke risk in non-valvular atrial fibrillation, to treat deep vein thrombosis and pulmonary embolism, to prevent them from recurring, and to prevent clots after hip and knee replacement. Missing doses matters more than with warfarin because the effect wears off within a day or so. Bleeding is the main risk, and it should never be stopped without the prescriber’s advice.

    Generic apixaban tablets have been approved by the FDA, but patent litigation settlements mean they are not expected on the US market until the second half of this decade. Until then, every pharmacy is dispensing the same brand product.

    Why the cash price for Apixaban differs from pharmacy to pharmacy

    Because apixaban is brand-only, every pharmacy pays roughly the same wholesale cost and the cash price difference between pharmacies is entirely margin. Chains tend to price at or above list; independent pharmacies competing for a long-term twice-daily prescription will often price much closer to their cost.

    The manufacturer offers a free-trial card and a co-pay card, both of which require commercial insurance, and a patient assistance programme for people below an income threshold. For a fully cash-paying patient who does not qualify, pharmacy competition is the main lever.

    Ways to pay less for Apixaban without insurance

    • Check whether you qualify for the manufacturer’s patient assistance programme before paying cash; the income thresholds are broader than many people assume.
    • If you have any commercial insurance, the manufacturer co-pay card usually beats any cash price.
    • Ask your prescriber about a ninety-day prescription; on a brand drug the dispensing fee is a small share, but some pharmacies discount longer fills.
    • Compare independent pharmacies; the margin they add on a brand product is often smaller than a chain’s.
    • Upload your prescription to Script Unlock so licensed pharmacies can quote their cash price. You pay the pharmacy directly.

    How Script Unlock gets you a cash price for Apixaban

    Prices on this site come from pharmacies responding to a real prescription. We do not publish estimated, average or "typical" prices, because none of those would be your price.

    1. 1You upload your prescription

      A photo of your Apixaban prescription is enough. Nothing is sold on the site; you are asking pharmacies to quote.

    2. 2Licensed pharmacies respond

      Pharmacies that Script Unlock has verified see the request and each can reply with its own cash price for your exact drug, strength and quantity.

    3. 3You choose and pay the pharmacy

      You compare the responses, pick a pharmacy, and pay that pharmacy directly when you collect. Script Unlock never takes a patient payment and never sets the price.

    Upload a Apixaban prescriptionWhat Script Unlock cannot do

    Questions to ask your pharmacist about Apixaban

    1. 1.What should I do if I miss a dose?
    2. 2.Which painkillers and supplements increase bleeding risk with apixaban?
    3. 3.What bleeding signs mean I should seek urgent care?
    4. 4.Do I need to stop it before dental work or surgery, and who decides?
    5. 5.Is my dose the standard or the reduced dose, and why?

    Related medications

    MetoprololLisinoprilAtorvastatinRivaroxabanDabigatran

    Sources

    • FDA-approved labeling on DailyMed (apixaban)
    • FDA Orange Book (approved generics and therapeutic equivalence)
    • MedlinePlus drug information (National Library of Medicine)

    Script Unlock is a marketplace that lets licensed pharmacies quote a cash price on your prescription. It does not prescribe, dispense or sell medication, does not process patient payments, and does not give medical advice. Always follow the instructions of your prescriber and pharmacist and read the medication guide supplied with your medicine.

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    Upload your prescription and licensed, verified pharmacies each quote their own cash price. You pay the pharmacy directly.

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