Inflammatory Bowel Disease (IBD) in Cats
Feline IBD is a chronic enteropathy diagnosed by biopsy after dietary trial. First-line therapy is hypoallergenic or hydrolyzed diet, followed by immunomodulation with prednisolone (preferred over prednisone in cats — better hepatic conversion).
Symptoms to watch for
- •Chronic vomiting (>3 weeks)
- •Chronic diarrhea (small or large bowel)
- •Weight loss
- •Variable appetite
- •Hematochezia or melena in severe cases
Treatment options
Preferred steroid in cats (don't use prednisone — cats convert it poorly). Compounded flavored suspension for long-term dosing.
Second-line immunosuppressant when prednisolone alone insufficient. Compounded mini-tabs.
For dysbiosis component; short courses preferred (neurotoxicity at high doses or chronic use).
B12 supplementation common (subcutaneous or oral) due to malabsorption.
Why compounded medication matters
Flavored prednisolone suspension is the workhorse of long-term IBD management. Chlorambucil mini-tabs (0.5 mg) enable safe dosing in 4-5kg cats.
See compounded prednisolone optionsValid vet prescription required · HIPAA-compliant · Free to pet owners
FAQs — Inflammatory Bowel Disease (IBD) in Cats
Sources & review
Reviewed by: ScriptUnlock Pharmacy Verification Team
Last reviewed: June 2026
Sources cited:
- • WSAVA GI Standardization Group
- • ACVIM Consensus on Chronic Enteropathy
- • Plumb's 10th ed.
This information is educational and does not substitute for veterinary advice. Always confirm diagnosis, dosing, and treatment plan with your veterinarian. ScriptUnlock connects pet owners to verified pharmacies; we do not provide veterinary advice.