Compounded Methimazole for Pets
Methimazole is the cornerstone treatment for feline hyperthyroidism — the most common feline endocrine disease. Daily lifelong oral tablets are difficult for many cats and owners. Compounded transdermal methimazole (applied to the inner pinna) provides equivalent thyroid control with dramatically better long-term compliance.
Why Chewy Pharmacy can't fulfil this prescription
Chewy stocks commercial methimazole tablets only. They do NOT offer transdermal compounding. For cats that resist daily tablets (most do), Chewy is not a workable long-term solution.
Compounded forms in our 503A pharmacy network
- ✓Transdermal PLO (pluronic lecithin organogel) gel — applied to inner ear pinna
- ✓Flavored liquid suspension (tuna, fish)
- ✓Custom-strength chewable treats for cats that won’t accept transdermal
Species-specific benefit
Transdermal methimazole on the inner pinna is the de facto standard of care for long-term feline hyperthyroidism management. Owners no longer need to pill their cat daily for years. Thyroid control is equivalent to oral tablets per published ACVIM data.
Valid vet prescription required · HIPAA-compliant · Free to patients
FAQs — Compounded Methimazole
Sources & review
Reviewed by: ScriptUnlock Pharmacy Verification Team
Last reviewed: June 2026
Sources cited:
- • ACVIM feline endocrinology consensus
- • ISFM hyperthyroidism guidelines
- • Trepanier 2007 transdermal methimazole study
Always confirm dosing and indications with your veterinarian. Compounded medications are prescribed and prepared per the individual patient. ScriptUnlock connects you to verified 503A compounding pharmacies; we do not provide veterinary advice.