Thymosin Alpha-1
Thymalfasin
Thymosin Alpha-1 (Tα1) is a thymic peptide that modulates immune function. It is FDA-orphan designated and approved in over 30 countries for hepatitis B/C and as an immune adjuvant.
Pricing Overview
Brand / Retail Price
$200–$600/month (Zadaxin brand)
Compounded / Cash Pay
$100–$300/month
Compounding pharmacies offer significant savings over the Zadaxin brand
Primary Uses
How Thymosin Alpha-1 Works
Tα1 enhances T-cell maturation, promotes dendritic cell differentiation, modulates cytokine production, and activates natural killer (NK) cells. It rebalances immune function rather than simply boosting it.
Dosing Information
Typical Dose
1.6mg 2x/week
Frequency
Twice weekly
Administration
Subcutaneous injection
Notes
Standard protocol: 1.6mg twice weekly for 6–12 months
Side Effects & Safety
Common
- • Injection site reactions
- • Mild fatigue (immune activation)
Serious
- • Very well-tolerated — extensive safety data from international use
Rare
- • Allergic reactions
- • Temporary immune flare
Frequently Asked Questions
Is Thymosin Alpha-1 FDA approved?
Tα1 has FDA orphan drug designation but is not fully FDA-approved in the US. It is approved in 35+ countries. US patients access it through compounding pharmacies with a physician prescription.
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