Semax
Semax (MEHFPGP)
Semax is a synthetic peptide analog of ACTH (4-10) developed by the Russian Academy of Sciences. It is a potent nootropic and neuroprotective agent approved in Russia for cognitive enhancement and stroke recovery.
Pricing Overview
Brand / Retail Price
N/A
Compounded / Cash Pay
$60–$200/month
Premium nootropic at fraction of prescription cognitive medication costs
Primary Uses
How Semax Works
Semax increases BDNF (brain-derived neurotrophic factor) levels by 300–800%, enhances dopamine and serotonin neurotransmission, provides neuroprotection through anti-inflammatory mechanisms, and improves cerebral blood flow.
Dosing Information
Typical Dose
200–600mcg daily
Frequency
1–3 times daily
Administration
Intranasal spray
Notes
N-Acetyl Semax Amidate (NASA) version has enhanced bioavailability
Side Effects & Safety
Common
- • Nasal dryness
- • Mild headache (initial)
- • Occasional irritability
Serious
- • Very few reported — decades of use in Russia
Rare
- • Hair thinning at very high doses
- • Overstimulation
Frequently Asked Questions
Can Semax help with ADHD?
Semax increases dopamine and BDNF, which may improve focus and attention. Some users report benefits comparable to low-dose stimulant medications. However, it is not FDA-approved for ADHD and should not replace prescribed treatment without medical guidance.
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