MK-677 (Ibutamoren)
Ibutamoren Mesylate
MK-677 (Ibutamoren) is an oral growth hormone secretagogue that mimics ghrelin and stimulates sustained GH and IGF-1 release. Unlike injectable peptides, it is taken orally.
Pricing Overview
Brand / Retail Price
N/A (research compound)
Compounded / Cash Pay
$50–$150/month
Most affordable GH secretagogue — oral convenience vs injectable peptides
Primary Uses
How MK-677 (Ibutamoren) Works
MK-677 activates the ghrelin receptor (GHSR), stimulating growth hormone release from the pituitary. It also increases IGF-1 levels and promotes deeper sleep stages associated with GH pulses.
Dosing Information
Typical Dose
10–25mg daily
Frequency
Once daily (oral)
Administration
Oral capsule or liquid
Notes
Take at bedtime to leverage natural GH pulse and minimize appetite stimulation during the day
Side Effects & Safety
Common
- • Increased appetite
- • Water retention/bloating
- • Numbness/tingling
- • Elevated blood sugar
Serious
- • Insulin resistance (long-term)
- • Elevated fasting glucose
- • Potential impact on blood pressure
Rare
- • Joint pain
- • Lethargy
Frequently Asked Questions
Is MK-677 a steroid or SARM?
No, MK-677 is neither a steroid nor a SARM. It is a growth hormone secretagogue (GHS) that stimulates GH release through the ghrelin receptor. It does not interact with androgen receptors.
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