Dulaglutide
Dulaglutide
Dulaglutide (Trulicity) is a once-weekly GLP-1 receptor agonist for type 2 diabetes with proven cardiovascular benefits.
Pricing Overview
Brand / Retail Price
$800–$1,200/month
Compounded / Cash Pay
$150–$400/month
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Primary Uses
How Dulaglutide Works
Dulaglutide consists of a GLP-1 analog covalently linked to a modified IgG4 Fc fragment, extending its half-life for weekly dosing while activating GLP-1 receptors.
Dosing Information
Typical Dose
0.75mg–4.5mg weekly
Frequency
Once weekly
Administration
Subcutaneous injection (pre-filled pen)
Side Effects & Safety
Common
- • Nausea
- • Diarrhea
- • Vomiting
- • Abdominal pain
Serious
- • Pancreatitis
- • Thyroid C-cell tumors (animal studies)
- • Hypoglycemia
Rare
- • Anaphylaxis
- • Angioedema
Frequently Asked Questions
How does Trulicity compare to Ozempic?
Both are weekly GLP-1 injections. Ozempic (semaglutide) generally shows greater A1C reduction and weight loss, but Trulicity (dulaglutide) has strong cardiovascular outcomes data and may be more affordable.
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