Lisinopril Side Effects
Common and serious side effects of Lisinopril (Lisinopril) — what to expect and how to manage them.
Common Side Effects
- Dry, persistent cough (10-15% of patients — due to bradykinin accumulation)
- Dizziness or lightheadedness (especially first dose)
- Headache
- Fatigue
- Nausea
Serious Side Effects
Seek immediate care if severe- Angioedema (rapid swelling of face, lips, tongue, throat — MEDICAL EMERGENCY, call 911)
- Hyperkalemia (dangerously high potassium)
- Acute kidney injury (especially with bilateral renal artery stenosis, severe dehydration)
- Severe hypotension (first dose — sit/lie down after first dose)
- Teratogenicity (NEVER use in pregnancy — causes fetal kidney damage and death)
Managing Side Effects
- Persistent cough? Ask about switching to an ARB (e.g., losartan) — same heart/kidney benefits, no cough
- Take first dose at bedtime to reduce dizziness
- Rise slowly from sitting or lying position
- Avoid potassium supplements, potassium-sparing diuretics, and salt substitutes (KCl)
- If face/throat swelling occurs, call 911 immediately
What Your Doctor May Monitor
Blood pressure (including orthostatic)Potassium and kidney function (creatinine/eGFR) — recheck 1-2 weeks after startingSigns of angioedema
Lisinopril Cash Price
Lisinopril cash prices start from $9 when pharmacies compete on Script Unlock — up to 75% below retail. No insurance required.
Compare Lisinopril PricesMedical Disclaimer: This information is for educational reference only. Side effects vary by individual, dose, and other medications. Always consult your healthcare provider for personalized medical advice. Do not stop or change your medication without medical guidance.