Tirzepatide Alternatives in California
Compare generic and therapeutic alternatives to Tirzepatide (tirzepatide) available at California pharmacies. Save up to 38% on your prescription — no insurance required.
Top Alternatives in California
Semaglutide (Ozempic/Wegovy)
therapeutic
GLP-1 agonist — well-established, slightly lower weight loss on average
Avg cash price: $940/mo
Compounded tirzepatide
therapeutic
Compounding pharmacy option — available during FDA shortage periods
Avg cash price: $300/mo
Rybelsus (oral semaglutide)
therapeutic
Oral daily tablet — no injection, moderate weight loss
Avg cash price: $870/mo
California Prescription Assistance Programs
Medi-Cal Rx
Comprehensive outpatient prescription drug coverage for Medi-Cal beneficiaries, including generic and brand-name medications on the formulary.
Eligibility: California Medicaid (Medi-Cal) enrollees. Income limits vary by category; generally up to 138% FPL for adults.
GHPP (Genetically Handicapped Persons Program)
Prescription drugs and medical services for individuals with covered genetic conditions including cystic fibrosis, hemophilia, PKU, sickle cell disease, and others.
Eligibility: California residents with a diagnosed covered genetic condition; income-based co-pays apply.
Frequently Asked Questions
What is the difference between Mounjaro and Zepbound?
Mounjaro and Zepbound contain identical tirzepatide. Mounjaro is FDA-approved for type 2 diabetes; Zepbound is FDA-approved for chronic weight management/obesity. Same drug, different labelled indication.
How much weight loss can I expect on tirzepatide?
The SURMOUNT trials showed average weight loss of 15–22.5% of body weight on tirzepatide 10–15 mg/week — greater than any other approved weight-loss medication and comparable to bariatric surgery outcomes.
How does tirzepatide differ from semaglutide?
Tirzepatide targets both GLP-1 and GIP receptors; semaglutide only targets GLP-1. The dual mechanism of tirzepatide produces greater average weight loss and HbA1c reduction in head-to-head trials (SURPASS-2).
Is there a cheaper alternative to tirzepatide?
Compounded tirzepatide from licensed pharmacies costs $250–$400/month during FDA shortage periods — 60–75% less than brand Mounjaro/Zepbound. Confirm current shortage status with your pharmacist.
Can Script Unlock help with tirzepatide costs?
Script Unlock connects patients with pharmacies carrying brand Mounjaro/Zepbound and compounding pharmacies offering tirzepatide during shortage periods. Post your prescription to compare bids.