Tadalafil Alternatives in California
Compare generic and therapeutic alternatives to Tadalafil (tadalafil) available at California pharmacies. Save up to 92% on your prescription — no insurance required.
Top Alternatives in California
Sildenafil (generic Viagra)
therapeutic
Shorter-acting PDE5 inhibitor — 4-6 hours vs 36 hours
Avg cash price: $20/mo
Vardenafil (generic Levitra)
therapeutic
Similar profile to sildenafil — slightly longer duration
Avg cash price: $40/mo
Cialis (brand tadalafil)
brand
Brand name — same drug at 12× the cost
Avg cash price: $380/mo
California Prescription Assistance Programs
Medi-Cal Rx
Comprehensive outpatient prescription drug coverage for Medi-Cal beneficiaries, including generic and brand-name medications on the formulary.
Eligibility: California Medicaid (Medi-Cal) enrollees. Income limits vary by category; generally up to 138% FPL for adults.
GHPP (Genetically Handicapped Persons Program)
Prescription drugs and medical services for individuals with covered genetic conditions including cystic fibrosis, hemophilia, PKU, sickle cell disease, and others.
Eligibility: California residents with a diagnosed covered genetic condition; income-based co-pays apply.
Frequently Asked Questions
Is tadalafil the same as Cialis?
Yes — tadalafil is the generic form of Cialis. It has been generic in the US since 2018 and typically costs $20–$40/month versus $350+ for brand Cialis.
What is the difference between 5 mg daily tadalafil and 20 mg on-demand tadalafil?
Daily low-dose tadalafil (2.5–5 mg) maintains a steady state for continuous ED management and also treats BPH symptoms. On-demand 10–20 mg provides a 36-hour window when taken before activity.
Can tadalafil treat enlarged prostate (BPH)?
Yes — tadalafil 5 mg daily is FDA-approved for benign prostatic hyperplasia and can be used for both BPH and ED simultaneously. It relaxes smooth muscle in the bladder neck and prostate.
Why does tadalafil last longer than sildenafil?
Tadalafil has a half-life of 17.5 hours versus ~4 hours for sildenafil. This extended duration (up to 36 hours) is why it is called "the weekend pill." It does not cause continuous erections — stimulation is still required.
What does generic tadalafil cost through Script Unlock?
Generic tadalafil is typically $20–$35/month through Script Unlock pharmacies — one of the best generic value propositions for ED treatment.