Simvastatin Alternatives in South Dakota
Compare generic and therapeutic alternatives to Simvastatin (simvastatin) available at South Dakota pharmacies. Save up to 94% on your prescription — no insurance required.
Top Alternatives in South Dakota
Atorvastatin (generic Lipitor)
therapeutic
High-intensity statin — more potent at similar doses
Avg cash price: $12/mo
Rosuvastatin (generic Crestor)
therapeutic
Most potent statin per mg — useful at low doses
Avg cash price: $15/mo
Zocor (brand simvastatin)
brand
Brand name — same drug at 30× the cost
Avg cash price: $240/mo
South Dakota Prescription Assistance Programs
South Dakota Medicaid Rx
Prescription drug coverage for South Dakota Medicaid beneficiaries.
Eligibility: South Dakota expanded Medicaid in 2023 (via ballot measure). Low-income adults up to 138% FPL, children, pregnant women, and people with disabilities.
Frequently Asked Questions
Is simvastatin the same as Zocor?
Yes — simvastatin is the generic form of Zocor. It has been generic since 2006 and costs $5–$12/month versus $220–$260 for brand Zocor.
Why did my doctor switch me from simvastatin to atorvastatin?
The FDA recommends limiting simvastatin 80 mg due to high muscle injury (myopathy) risk. Atorvastatin 40–80 mg achieves greater LDL reduction with a better safety profile, prompting many switches.
What drug interactions does simvastatin have?
Simvastatin is metabolised by CYP3A4, making it susceptible to interactions with many drugs including certain antibiotics (clarithromycin, erythromycin), antifungals, and grapefruit juice — which can dramatically increase simvastatin blood levels and muscle injury risk.
Does simvastatin have to be taken at night?
Yes — simvastatin should ideally be taken in the evening, as cholesterol synthesis peaks overnight. Unlike rosuvastatin and atorvastatin (long half-lives), simvastatin timing matters more for optimal efficacy.
What does simvastatin cost through Script Unlock?
Simvastatin is one of the cheapest medications — typically $5–$10/month through Script Unlock pharmacies. It remains a cost-effective choice for moderate cholesterol lowering.