Simvastatin Alternatives in Missouri
Compare generic and therapeutic alternatives to Simvastatin (simvastatin) available at Missouri pharmacies. Save up to 94% on your prescription — no insurance required.
Top Alternatives in Missouri
Atorvastatin (generic Lipitor)
therapeutic
High-intensity statin — more potent at similar doses
Avg cash price: $12/mo
Rosuvastatin (generic Crestor)
therapeutic
Most potent statin per mg — useful at low doses
Avg cash price: $15/mo
Zocor (brand simvastatin)
brand
Brand name — same drug at 30× the cost
Avg cash price: $240/mo
Missouri Prescription Assistance Programs
MO HealthNet (Missouri Medicaid)
Prescription drug coverage for MO HealthNet (Missouri Medicaid) enrollees.
Eligibility: Low-income Missouri residents including children, pregnant women, seniors, and people with disabilities. Missouri voted to expand Medicaid in 2020.
Frequently Asked Questions
Is simvastatin the same as Zocor?
Yes — simvastatin is the generic form of Zocor. It has been generic since 2006 and costs $5–$12/month versus $220–$260 for brand Zocor.
Why did my doctor switch me from simvastatin to atorvastatin?
The FDA recommends limiting simvastatin 80 mg due to high muscle injury (myopathy) risk. Atorvastatin 40–80 mg achieves greater LDL reduction with a better safety profile, prompting many switches.
What drug interactions does simvastatin have?
Simvastatin is metabolised by CYP3A4, making it susceptible to interactions with many drugs including certain antibiotics (clarithromycin, erythromycin), antifungals, and grapefruit juice — which can dramatically increase simvastatin blood levels and muscle injury risk.
Does simvastatin have to be taken at night?
Yes — simvastatin should ideally be taken in the evening, as cholesterol synthesis peaks overnight. Unlike rosuvastatin and atorvastatin (long half-lives), simvastatin timing matters more for optimal efficacy.
What does simvastatin cost through Script Unlock?
Simvastatin is one of the cheapest medications — typically $5–$10/month through Script Unlock pharmacies. It remains a cost-effective choice for moderate cholesterol lowering.