Sertraline Alternatives in South Dakota
Compare generic and therapeutic alternatives to Sertraline (sertraline hydrochloride) available at South Dakota pharmacies. Save up to 93% on your prescription — no insurance required.
Top Alternatives in South Dakota
Escitalopram (generic Lexapro)
therapeutic
Highly selective SSRI — fewer drug interactions, similarly priced
Avg cash price: $12/mo
Fluoxetine (generic Prozac)
therapeutic
Long half-life SSRI — most forgiving of missed doses
Avg cash price: $8/mo
Zoloft (brand sertraline)
brand
Brand name — same drug at over 25× the cost
Avg cash price: $280/mo
South Dakota Prescription Assistance Programs
South Dakota Medicaid Rx
Prescription drug coverage for South Dakota Medicaid beneficiaries.
Eligibility: South Dakota expanded Medicaid in 2023 (via ballot measure). Low-income adults up to 138% FPL, children, pregnant women, and people with disabilities.
Frequently Asked Questions
Is sertraline the same as Zoloft?
Yes — sertraline is the generic form of Zoloft. It has been generic since 2006 and costs $8–$15/month versus $250–$300 for brand Zoloft.
What conditions is sertraline approved for?
Sertraline has the broadest FDA approval of any SSRI — major depression, OCD, panic disorder, PTSD, social anxiety disorder, and premenstrual dysphoric disorder (PMDD).
Is sertraline or escitalopram better tolerated?
Both are among the best-tolerated SSRIs. Escitalopram has fewer drug interactions (less CYP inhibition); sertraline is considered slightly more likely to cause initial GI symptoms. Individual tolerability varies.
How long does it take for sertraline to work for anxiety?
Anxiety reduction typically begins at 2–4 weeks; full benefit for anxiety disorders (especially OCD and PTSD) may take 8–12 weeks. Do not discontinue early based on partial response.
What does generic sertraline cost through Script Unlock?
Sertraline is one of the most affordable psychiatric medications — typically $8–$14/month. Script Unlock pharmacies offer competitive cash pricing that frequently matches or beats discount card prices.