Omeprazole Alternatives in District of Columbia
Compare generic and therapeutic alternatives to Omeprazole (omeprazole) available at District of Columbia pharmacies. Save up to 92% on your prescription — no insurance required.
Top Alternatives in District of Columbia
Pantoprazole (generic Protonix)
therapeutic
Prescription PPI — slightly fewer drug interactions than omeprazole
Avg cash price: $8/mo
Esomeprazole (generic Nexium)
therapeutic
S-enantiomer of omeprazole — marginally longer duration
Avg cash price: $15/mo
Famotidine (generic Pepcid)
therapeutic
H2 blocker — OTC alternative, weaker acid suppression
Avg cash price: $8/mo
District of Columbia Prescription Assistance Programs
DC Medicaid Rx (DC Health Care Alliance)
Prescription drug coverage for DC Medicaid beneficiaries and uninsured DC residents with incomes up to 200% FPL through the DC Health Care Alliance program.
Eligibility: Low-income DC residents including adults up to 215% FPL for Medicaid, and uninsured adults through the Alliance program.
DCPAP (DC Pharmaceutical Assistance Program)
Assists eligible low-income DC seniors with Medicare Part D co-payments and coverage gaps.
Eligibility: DC residents aged 65+ enrolled in Medicare Part D with income at or below 300% FPL. Contact the DC Office on Aging at 202-724-5622.
Frequently Asked Questions
Is omeprazole the same as Prilosec?
Yes — omeprazole is the generic name for Prilosec. It is available both OTC and by prescription and typically costs $8–$15/month. Brand Prilosec OTC is the same drug at higher cost.
What is the difference between omeprazole and pantoprazole?
Both are PPIs with similar efficacy. Pantoprazole has fewer drug interactions (does not inhibit CYP2C19 as strongly), making it preferred for patients on clopidogrel (Plavix) or certain antidepressants.
Can I take omeprazole every day long-term?
Long-term daily PPI use raises modest risks: reduced B12, magnesium, and calcium absorption; slight increased fracture risk; and possible C. difficile susceptibility. Use the lowest effective dose for the shortest necessary duration.
Is omeprazole stronger than famotidine (Pepcid)?
Yes — PPIs like omeprazole provide more complete and sustained acid suppression than H2 blockers like famotidine. PPIs are preferred for GERD and ulcer healing; H2 blockers may suffice for mild heartburn.
What does omeprazole cost through Script Unlock?
Omeprazole is available OTC without a prescription for around $10–$15/month. Prescription-strength versions through Script Unlock pharmacies may offer even lower cash pricing.