Esomeprazole Alternatives in North Carolina
Compare generic and therapeutic alternatives to Esomeprazole (esomeprazole) available at North Carolina pharmacies. Save up to 94% on your prescription — no insurance required.
Top Alternatives in North Carolina
Omeprazole (generic Prilosec)
therapeutic
Closely related PPI — available OTC, very cheap
Avg cash price: $10/mo
Pantoprazole (generic Protonix)
therapeutic
Prescription PPI — one of the cheapest available
Avg cash price: $8/mo
Nexium (brand esomeprazole)
brand
Brand name — identical drug at 15× the cost
Avg cash price: $240/mo
North Carolina Prescription Assistance Programs
NC Medicaid Rx
Prescription drug coverage for NC Medicaid and NC Health Choice (CHIP) beneficiaries.
Eligibility: Low-income North Carolina adults, children, pregnant women, seniors, and people with disabilities. North Carolina expanded Medicaid in December 2023.
Frequently Asked Questions
Is esomeprazole the same as Nexium?
Esomeprazole is the generic form of Nexium. It is bioequivalent and costs $10–$20/month. Brand Nexium can cost $200–$260/month — making the generic one of the largest cost-saving switches.
What is the difference between esomeprazole and omeprazole?
Esomeprazole is the S-enantiomer of omeprazole. At equivalent doses, clinical outcomes are essentially identical for most patients. Both are excellent PPI options.
Can I take esomeprazole long-term?
Long-term PPI use (>1 year) is associated with modest risks including B12 deficiency, hypomagnesaemia, and increased fracture risk. Use the lowest effective dose for the shortest duration needed.
Is OTC omeprazole as good as prescription esomeprazole?
For most GERD and heartburn patients, yes. OTC omeprazole 20 mg works as well as prescription esomeprazole for typical reflux. Discuss with your doctor if you have complex or severe symptoms.
What does generic esomeprazole cost through Script Unlock?
Generic esomeprazole through Script Unlock pharmacies typically costs $10–$18/month — comparable to or cheaper than most discount card prices.