90-Day Supply · Save Up To $1444/Year
Esketamine 90-Day Supply — Save $1444/Year vs Monthly Fills
For chronic Esketamine (Esketamine Hydrochloride) patients, a 90-day supply is the single biggest lever to reduce annual prescription costs. ScriptUnlock pharmacies fill 90-day supplies of Esketamine from $1808 — cutting your fills from 12/year to 4/year and saving meaningful money.
Monthly fill × 12
$8676
$723/mo
90-day × 4
$7232
$1808/quarter
You save
$1444/yr
≈17% off
The math: monthly vs 90-day Esketamine
Monthly Esketamine: $723 × 12 fills/year= $8676/year
90-day Esketamine: $1808 × 4 fills/year= $7232/year
Annual savings:$1444
Per-dose cost (monthly): $24.10Per-dose (90-day): $20.09
Side-by-side: Esketamine cost comparison
12× Monthly Fills
$8676
- • 12 pharmacy trips per year
- • 12 dispensing fees
- • 12 chances to run out
- • Higher per-dose cost
4× 90-Day Fills · Recommended
$7232
- • 4 pharmacy trips per year
- • 4 dispensing fees
- • Less risk of missed doses
- • Lower per-dose cost
Who benefits most from 90-day Esketamine
90-day supplies are designed for stable, maintenance medications. Esketamine is ideal for 90-day fills if you have:
Type 2 Diabetes
Metformin, Esketamine, and other diabetes meds are taken long-term — perfect 90-day candidates.
High Blood Pressure
Lifelong therapy — 90-day fills reduce both cost and missed doses.
High Cholesterol
Statins are typically permanent therapy — 90-day fills save real money.
Hypothyroidism
Stable dosing once titrated — ideal for 90-day refills.
Mental Health (SSRI / SNRI)
Consistent medication availability reduces relapse risk.
Asthma / COPD maintenance
Daily controller inhalers and tablets work well as 90-day supplies.
Does my pharmacy offer 90-day supplies of Esketamine?
Most chain pharmacies (CVS, Walgreens, Walmart, Costco) and nearly all independents will fill a 90-day supply of Esketamineif your prescription is written for it. Things that can block a 90-day fill:
- Prescription written for "30 days, 11 refills" — ask prescriber to rewrite as "90 days, 3 refills".
- Insurance plans that require 30-day fills for the first 90 days of a new medication (stability rule).
- Controlled substances (C-II) — typically capped at 30-day supply by federal law.
ScriptUnlock workaround: if your usual pharmacy won't fill 90-day, our partner network includes pharmacies that specialize in 90-day chronic-care fulfillment.
Mail order vs local pharmacy for 90-day Esketamine
Mail Order 90-Day
- ✓ Delivered to your door, every 90 days
- ✓ Often the cheapest cash price
- ✓ Auto-refill on schedule
- ✗ 3–7 day shipping delay on first fill
- ✗ Less personal pharmacist relationship
Best for: stable, predictable refills.
Local 90-Day Pickup
- ✓ Same-day pickup possible
- ✓ Pharmacist available for questions
- ✓ Easier to handle dose changes
- ✗ Slightly higher cash price (usually)
- ✗ You must remember to refill
Best for: complex regimens, newer Rx.
Switch to 90-day Esketamine and save $1444/year
Upload your prescription — ScriptUnlock pharmacies bid on 90-day fills from $1808.
Get 90-Day Esketamine Prices90-day Esketamine FAQs
Is a 90-day supply of Esketamine cheaper than monthly?
Yes. A 90-day supply of Esketamine (Esketamine Hydrochloride) on ScriptUnlock costs approximately $1808 — versus $2169 for three separate monthly fills. That's a saving of $361 per quarter, or about $1444 per year. The savings come from lower dispensing fees and pharmacy efficiency on larger fills.
Can I get a 90-day supply of Esketamine without insurance?
Absolutely. ScriptUnlock is built for cash-pay patients — you can fill a 90-day supply of Esketamine for $1808 without any insurance, membership, or discount card. Cash prices on ScriptUnlock are often lower than insurance copays for Esketamine.
How do I switch to 90-day fills for Esketamine?
Ask your prescriber to write your next Esketamine prescription as a 90-day supply (e.g. "Esketamine Hydrochloride #90, 1 tablet daily, 3 refills"). Most maintenance medications are eligible. Upload the new prescription to ScriptUnlock and pharmacies will bid on the 90-day fill.
Does ScriptUnlock offer 90-day supplies?
Yes — ScriptUnlock partner pharmacies routinely fill 90-day supplies of Esketamine and most chronic-care medications. Both local pickup and mail-order 90-day fulfillment are available, depending on your zip code and the bidding pharmacies.
What's the cheapest way to get a 90-day supply of Esketamine?
The cheapest 90-day supply of Esketamine is typically through ScriptUnlock cash bidding from $1808. Compare against your insurance copay × 3 (most plans charge full copay per 30-day fill). For most patients, cash 90-day on ScriptUnlock beats insurance by $361–$1444 per year.